World’s Most Activated Enzymes™

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“I tried many digestive enzymes without success these got rid of mid-day pregnant belly bloating*”

Amy, California * Results atypical, Individual results will vary

Feel the Relief Our ‘Activated Enzymes’ In the First Day

Our fully activated HoloZymes reduce occasional gut related complaints including gas, bloating, loose stools, undigested foods, tummy pain, and cramping. *

Most of our customers feel the difference right away…

  • Fast Acting
  • Patent Proven Formula
  • All Natural
  • Clinically Proven (6 studies)
  • No Fillers
  • 100% Effective Range pH 1.7- pH 11.0
  • Professional Grade
  • Non-GMO

Digestive enzymes are special molecules that speed up the breakdown of food into usable nutrients. And when properly activated, some of these enzymes are absorbed into the body and help support a healthy immune system.

If foods are not properly broken down by enzymes, the consequences are typically felt. And “feeling” our digestion is typically a bad sign.

Why Enzymes Are Critical to Great Digestion

When we eat food, enzymes rush in to break the food down, after they do their job, we absorb the broken down carbohydrate, fat, and protein molecules.

However, without proper enzymes to do the hard work, bigger food pieces are left to ferment inside of us and feed extra gut bugs.

Which often means bloating, burping, gas, and other embarrassing issues.

It can mean digestion slows down or speeds wayyy up.

Over time, this leads to more disrupted gut bugs and less nutrients… which in turn, makes it harder and harder to produce enough digestive enzymes.

Not only that, but these 5 risk factors contribute to low digestive enzymes on their own:

  • Low stomach acid
  • Not chewing properly
  • Stress
  • The Aging Process
  • Traumas (physical or emotional)

It’s easy to see why in today’s world, most people’s digestion is struggling to keep up.

While digestive enzymes have been around for centuries, there’s one major problem that has prevented them from reliably working.

The Truth About Why Our Enzymes Are Better

Over the last 10 years we’ve tested over 30 brands of digestive enzymes. Some helped a little, some didn’t, and we were always left wondering…


How could name brands, with great reputations… deliver such inconsistent results?

Then we meet a PhD researcher who was awarded a patent for marrying the right “activators” or “cofactors” to a specific blend of 4x concentrated enzymes.

Suddenly it all made sense.

The problem with Digestive Enzymes is that they each must be “activated” by very specific minerals in order to do their magic.

And unless the “activation” is in the supplement… it’s only by chance they work.

The first time the PhD researcher told me this, I didn’t believe him…

But Together, We’ve Solved The ‘Activation Problem’

This PhD researcher found that each specific enzyme needs the right mineral cofactor to be turned on. And he found that the specific quantity and type of mineral made a remarkable difference in how well each of the enzymes worked.

So after years of trial and error, he figured out the specific enzyme strain and perfect mineral cofactor that, when married together, created the most activated enzyme in the world.

He had to do this for each enzyme strain and make sure it would work no matter what.

It took years to develop these specific minerals and ratios.

He needed to make sure it worked anywhere in the body. Once he cracked the code he filed a patent… but they didn’t believe him, so he proved it with 6 pilot clinical trials.

What a blessing it was to find his work. I’d already spent a year trying to build the most powerful enzyme ever created.

Company after company told me it wasn’t possible… that it would cost $100.00’s a bottle. And then as fate would have it, I was introduced to this PhD researcher.

After hours on the phone and trying samples.

He proved me wrong. He proved everyone wrong… but no one had heard about it. So we partnered together and HoloZyme was born.

“These Enzymes Changed My Life. After trying 30 different enzymes in the last year, I finally found my enzyme for life. The activation really worked for me when most others didn’t. I’m so excited to share them with others” *

Steven Wright * Results atypical, Individual results will vary

Backed by 6 Pilot Clinical Studies… The Only Patented “Activated Enzyme” Formula Is Finally Here…

Most supplements are never patented or even clinically tested. Why?

Because it costs the company anywhere from $50,000 to $250,000 for a basic study. And unlike pharmaceutical companies, supplement companies just don’t have millions of dollars to prove results.

Which makes this formula even more rare.

In order to get it patented, it needed to prove that it was different than other enzymes.

The following 6 pilot studies were completed:

Pilot Study 1: 12 Person Placebo Controlled 30 Day Pilot Study Shows 18% Reduction in Blood Sugar

Pilot Study 2: 5 Person, High Fat Meal Shows Average of 16.8% decrease in Triglycerides

Pilot Study 3: 7 Person, 30 Day Study Shows 4.5% to 22.8% Reduction in Triglyceride Levels after Meals

Pilot Study 4: 60 Person, 21 Day, showed a 26% drop in blood triglyceride levels, almost 19% drop in RLP Cholesterol, a 9.8% drop in NEFA fats and an over 30% reduction in PAI-1.

Pilot Study 5: 3 Person Trial Shows Serum Uric Acid Decrease

Pilot Study 6: 5 person, 37% Reduction in High Uric Acid Levels for Patients

Please note: results vary, these pilot study results do not mean you will have the same results. The studies are preliminary and in order to make any claims, would need to be replicated with much bigger studies.

At this point, all that can be concluded is that in pilot studies HoloZyme™ does improve carbohydrate, fat, and protein digestion and it can be used systematically if taken on an empty stomach.

HoloZyme’s Patented Professional Ingredients Include:

  • AES ® Patented Absorption Technology – prevents enzymes from being destroyed by stomach acid, activates each specific enzyme to turn on at the right time and organic trace minerals to support gut health
  • Activ-Blend™ – 4x concentrated, dual hybrid enzyme strains, designed to work from ph 1.7 to ph 11.0 in the body.
  • Activ-Blend™ Protease – pancreatic enzyme breaks proteins down
  • Activ-Blend™ Amylase – pancreatic enzyme breaks carbohydrates down
  • Activ-Blend™ Lipase – pancreatic enzyme breaks fats down
  • Activ-Blend™ Lactase – brush border enzyme breaks lactose sugar down
  • Activ-Blend™ Cellulase – group of cellulose and fiber breakdown enzymes
  • Activ-Blend™ Sucrase – brush border enzyme breaks sucrose sugars like cane sugar down down glucose and fructose
  • Activ-Blend™ Maltase – brush border enzyme breaks maltose sugars down to glucose
  • Activ-Blend™ Alpha-Galactosidase – brush border enzyme breaks down fibers in legumes and vegetables
  • Kelp – important source of trace minerals and co-factors

How to Take HoloZyme

  • Regular: 2 per meal 3x per day
  • Anti-Aging: 2 per meal 3x per day, 2 before bed
  • Banged up: 4 per meal 3x per day, 4 before bed
  • Flare up: 6 per meal 3x per day, 6 before bed

Video Testimonials

“Mid-day Pregnant belly
Bloating is Gone”

Amy, California

“I was surprised
to find relief”

Alyssa, Colorado

“I can eat pizza again
without issues”

Christina, South Carolina

Choose the 6-Bottle Package
(Or The Package That’s Right For You) Below…

3 Bottles


One-Time Payment:

+ FREE Shipping*

Best Deal

6 Bottles


One-Time Payment:

+ FREE Shipping*

1 Bottle


One-Time Payment:

+ $9.95 Shipping*

Choose the 6-Bottle Package
(Or The Package That’s Right For You) Below…

Best Deal

6 Bottles


One-Time Payment:

+ FREE Shipping*

3 Bottles


One-Time Payment:

+ FREE Shipping*

1 Bottle


One-Time Payment:

+ $9.95 Shipping*

Digest Gold

Enzyme Activation Patent
Clinical Studies
Specific mineral activation235mg
Broad Mineral activation43mg25mg35mg
Broad Ph Range
Alpha-Galactosidase enzyme
Protein breakdown
Fat breakdown
Carbohydrate breakdown
Plant cellulose breakdown
Sucrose breakdown
Lactose breakdown
Maltose breakdown
Non animal derived enzymes
No fillers / no Additives
Gluten / Dairy free
Refund60 Days30 Days365 Days
Shelf Life2 Years
Private Support Group

Frequently Asked Questions

Q1: Who is HoloZyme For?

A: HoloZyme is for anyone who wants the digestive and systemic healing of enzymes. It’s for anyone who’s digestion is too fast, to much gas, bloat, loose, or sour. It helps get all the precious nutrients from every food you eat.

It’s for anyone who wants to systematically use enzymes to support immune function and healthy aging.

Anyone into anti-aging ideas and wanting to feel and look their best should consider HoloZyme as it has been shown to support protein, fat, and carbohydrate absorption in the body in healthy levels in 6 pilot studies.

It is especially helpful for anyone who has long standing digestive issues and or pain related complaints.

Q2: What makes HoloZyme different than other enzyme products I’ve tried?

A: It starts with the fact that HoloZyme is the most activated enzyme on the market. It was awarded a patent for its specific activation system. This ALONE make it totally different than all the other enzymes on the market.

We’ve tried all the other brands as well and we ended up licensing these patents in order to make the most activated enzyme on the market.

Why does activation matter?

Because each enzyme needs energy to “turn on” or “activate”. This energy comes from what is called a mineral co-factor. See enzymes are deactivated until they are gifted energy to work. HoloZyme includes this energy right in the capsule versus other brands who rely on the body to do the work.

If the body lacks the co-factors to “turn-on” the enzymes it is likely to stay deactivated.

Also our Activ-Blend ™ base enzymes are dual strain and 4x concentrated and work anywhere in a pH of 1.7 to a pH of 11.0. This allows this to work anywhere in the body unlike traditional pancreatin and many other enzymes who only work in narrow pH ranges.

We include the highest ingredients in enzymes and therefore need less of them.

Q3 – What are the ingredients in HoloZyme ?


Q4 – Is there Gluten, Dairy, Soy, Sugar, or GMO’s in HCL Guard+?

A: No. HoloZyme does NOT contain any major allergens, zero sugar, and is GMO free.

Q5 – How long will today’s special pricing be available?

A: We are unable to guarantee today’s special offer beyond midnight today. Once word gets out about our Best Deal, there’ll be a mad rush.

Supplies are limited and once it’s gone, so is this special deal.

Q6 – When will my order arrive?

A: When you order you will instantly receive an order confirmation email. You can relax then because we are working hard to get your order out the door to you as quickly as possible!

We will ship your order directly to your home or office using a premium mail carrier and you will have it within 5 to 10 business days of placing your order.

Products are shipped from Texas, USA and we will send you a shipment notification email with tracking number as soon as your order ships so that you can track it right to your door.

Q7 – What’s the refund policy?

A: Your order is backed by a 60-day money-back guarantees.

If you don’t like HoloZyme for any reason, email, or call us and we’ll start the refund process.

We’ll send you an RMA and shipping label and soon as you send us the unopened bottles back we’ll issue your money back minus shipping and handling fees.

Q8 – Is it safe to buy online?

A: Buying online is now one of the safest ways to shop! Special SSL Certificates authenticate our identity and encrypt the information of visitors who enter on our site.

This keeps thieves from “snooping” or “grabbing” any exchange between our Web page and another computer. When an SSL Certificate is installed, you can rest assured that the information you send is secured and can’t be viewed by cyber crooks.

You can know this by looking in the upper part of the screen.

Depending on your device you’ll see a padlock icon in the browser’s status bar and the “HTTPS://” prefix in the URL.

These are the signs that a secure handshake is happening between your device and our website. When the handshake is happening as it is now… you are safe.

We use a third-party credit card processor that meets the strictest international standards for data security to manage our credit card payments, so no one ever has access to your credit card information.

We do NOT keep your credit card number on file.

At Healthy Gut Nutrition, we take this very seriously are always doing our best to make this the safest and most secure way for you to shop.

Q9 – What is the shelf-life of HoloZyme ?

A: Each bottle is good for 2 years from the date of manufacturing. An order placed today will be good for at least 18-20 months depending on that date.

Q10 – If I live in California, does this fall under Prop65?

A: For more information of California’s Prop65 please click here.

Healthy Gut Nutrition’s claims to support digestion come from its ingredients and its ingredient’s respective studies, as well as anecdotal experiences of customers. The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease.

The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise, or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

* Results featured on this web site are atypical. As individuals differ, so will results.