“Enjoy the freedom to eat your favorite histamine-containing foods and drinks!” –Steven Wright

If you get fatigued, flushed, or foggy after eating, HistaHarmony, DAO (Diamine Oxidase) enzyme may help. HistaHarmony™ lets you enjoy even a glass of wine without histamine-related headaches. At home or on the go, keep HistaHarmony™ close by so you can eat the foods you love without paying for it later!

  • Powerful DAO enzyme to support the healthy breakdown of histamine
  • Helps reduce histamine reactions and histamine intolerance symptoms
  • Using patented ProDAOX™ with proprietary enzyme-preserving technology
  • Protected to your small intestine in enteric-coated tablets (others open in the stomach)

HistaHarmony™ helps your body degrade food-derived histamine and maintains healthy DAO levels in the digestive tract.

Our formula uses a high-potency DAO backed by 96 patents. We encapsulate the fragile enzyme using the best technology on the market, delivering more DAO where it needs to go in the gut. Then we nitrogen pack it to keep it fresh so you can trust you’re getting exactly what you pay for.



Estimated Delivery: May 24 – May 28
International orders take longer


GMP certified with Professional grade ingredients


Love it or we’ll refund you

What Testers Are Saying…

“I had tried 3 different brands of DAO and found that it took about 2 weeks to build up in my system, and I had to use 2-3 times the dosage to get small improvements. When I switched to HistaHarmony, I had very noticeable improvements in my histamine symptoms the very first time I took a single dose. I used to get really flushed when I drank my afternoon coffee, and now I don’t have that issue anymore and can enjoy my coffee more freely!”

– Kim K. (Verified Tester)

“So far I’ve noticed an improvement in the mucus.  I still have it but no where near as bad as I was.  So far I’m quite pleased with the improvement.”

– Tammy M. (Verified Tester)

“Within just 1 day, I felt SO much relief. I couldn’t believe how fast-acting this teeny tiny pill was. And within only 2 days…I was off all off Zyrtec and Benadryl, sleeping so much better, feeling more calm overall and have not taken antihistamines since. I can also see how it’s helping my nervous system feel more at ease and less under “threat” from external inflammatory triggers. So excited about this product!”

Laura B. (Verified Tester)

“Was having some kind of allergy flare yesterday and I was sneezing and sneezing and I took the HistaHarmony away from food and it stopped!” 

Janice C. (Verified Tester)

Sneezing, Itching, Headaches, Flushing Skin, Can’t Focus, and More: All Signs Your Histamine Bucket is Overflowing

Here’s what makes HistaHarmony™ more powerful than other DAO enzymes on the market:

As a result of the continuous improvement in the enzyme extraction and purification processes, HistaHarmony™is more efficient and has higher enzymatic activity than DAO offered by any competitors.

Researchers in Spain have been working on this specific DAO for over 15 years. 

Our source has numerous patents backing its therapeutic potential in the dietary management of DAO-deficiency-related conditions.

We use a proprietary, high-tech extraction process that preserves the DAO enzyme and delivers 20,000+ Histamine Degrading Units (HDUs) in every tablet.

More HDUs = more histamine-digesting power.

DAO enzymes are very fragile molecules. When they’re exposed to oxygen, light, moisture, or stomach acid, they can start to degrade and lose their potency quickly.

That’s why our DAO is nitrogen-packed in individual blister packs. Every tablet is preserved, right up until the moment you need it.

Compare this to a bottle full of capsules and only 1 oxygen absorber…Each time you pop open the cap, every DAO molecule is hit by light, oxygen, and moisture, further degrading its potency. 

That means by the time you get to the bottom of the bottle, your DAO may have lost a huge amount of its power.

HistaHarmony™is the only form of DAO on the market that uses enteric-coated tablet technology proven NOT to activate until it reaches the small intestine.

Why is this important?

DAO does its dirty work in the small intestine. If not enough DAO is present there, histamine can escape through the intestinal epithelium into the blood.

This is where most competitors fail.

No matter how potent their DAO is, if they’re not using this same technology, the enzymes will get destroyed by stomach acid before they make it to the small intestine.

That means you’d have to take a lot more pills to notice an improvement – or you may not feel anything at all.


Steven Wright

How to Use HistaHarmony

For food-related histamine reactions: Take 1 capsule 20 minutes before eating histamine-rich foods.

If you’re not seeing results with this method, experiment with taking HistaHarmony™at different times of the day.

For gut and full-body histamine support: Take 1 capsule at least 30 minutes away from meals or on an empty stomach when you usually experience histamine-related symptoms. For example, if you get flushed at night, take HistaHarmony™ before bedtime.

If your baseline histamine levels are already running high, you may experience more symptom relief and improved histamine tolerance by taking DAO away from food.

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Frequently Asked Questions

Who is HistaHarmony™ for?

HistaHarmony™ is for anyone experiencing reactions to high histamine foods or histamine intolerance symptoms. 

Additionally, if you have any of the following, you may also want to consider DAO supplementation:  

  • Mast Cell Activation Syndrome (MCAS)
  • Gut Inflammation  
  • Bowel Issues 
  • Gut Infections  
  • Mold Toxicity
  • Genetic variants for DAO (ABP1/AOC1 genes)

How long until I see results?

Depending on your overall histamine load, it could take several days to a few weeks to notice changes.

If you don’t notice results after a week or two, try changing the timing. For example, if you’ve been taking HistaHarmony™with meals, try taking it on an empty stomach (like before bed).

Should I combine DAO with a low-histamine diet?

If the histamine bucket is overflowing, a 30-day low-histamine diet can often be a game-changer for many people, and enough to make a difference. In the case of Mast Cell Activation Syndrome (MCAS), however, you may need to go longer (up to 6 months).

When combined with DAO supplementation, your results on a low-histamine diet will likely improve even more. Not only are you emptying the histamine bucket, but you’re also “patching” any holes.

Keep in mind that long-term, restrictive diets can lead to nutrient deficiencies and make gut issues worse if we are not careful. The goal is always to expand the diet. Plus, eating plenty of colorful veggies and fruits helps feed friendly gut microflora and butyrate producers!

Is there Gluten, Dairy, Soy, Sugar, or GMOs in HistaHarmony™?

No, none of Healthy Guts products contain any Gluten, Dairy, Soy, Sugar, or GMOs!

Who shouldn’t take HistaHarmony™?

HistaHarmony™ (and most DAO supplements) are derived from animal products. Ours is from porcine kidney extract (pork). So if you have a pork allergy or sensitivity, or avoid animal products for any reason, this product may not be right for you.

What’s the refund policy?

Your order is backed by a 60-day money-back guarantee.

If you don’t like this product for any reason, email, or call us and we’ll start the refund process.

We’ll send you an RMA and shipping label and as soon as you send us the unopened bottles back we’ll issue your money back minus shipping and handling fees.

Learn more about returns & refunds here.

When will my order arrive?

When you order you will instantly receive an order confirmation email. You can relax then because we are working hard to get your order out the door to you as quickly as possible!

We will ship your order directly to your home or office using a premium mail carrier and you will have it within 5 to 10 business days of placing your order.

Products are shipped from Chicago, USA and we will send you a shipment notification email with a tracking number as soon as your order ships so that you can track it right to your door.

Is it safe to buy online?

Buying online is now one of the safest ways to shop! Special SSL Certificates authenticate our identity and encrypt the information of visitors who enter our site.

This keeps thieves from “snooping” or “grabbing” any exchange between our Web page and another computer. When an SSL Certificate is installed, you can rest assured that the information you send is secured and can’t be viewed by cybercrooks.

You can know this by looking at the upper part of the screen. Depending on your device you’ll see a padlock icon in the browser’s status bar and the “HTTPS://” prefix in the URL.

These are the signs that a secure handshake is happening between your device and our website. When the handshake is happening as it is now… you are safe.

We use a third-party credit card processor that meets the strictest international standards for data security to manage our credit card payments, so no one ever has access to your credit card information. We do NOT keep your credit card number on file.

At Healthy Gut Nutrition, we take this very seriously and are always doing our best to make this the safest and most secure way for you to shop.

What is the shelf life of HistaHarmony™?

Each package is good for 2 years from the date of manufacturing. An order placed today will be good for at least 18-20 months depending on that date.

If I live in California, does this fall under Prop65?

Read more about California’s Prop65.