16+ Years Research
Clinician-formulated
Real-World Experience
16+ Years Research
Clinician-formulated
Real-World Experience
BEST SELLER
16+ Years Research
Clinician-formulated
Real-World Experience
60-Day HoloImmune™ Reset
Doctor-trusted
Clinically-Studied ingredients
"I have had less fatigue and a lot more good days than I had without HoloImmune, plus a chronic skin issue seems to be clearing"
– Kim
As seen in
Clinician-formulated. Science-backed ingredients.
87%
Experienced less bloating after meals
82%
Noticed reduction in gas
91%
Saw noticeable digestion improvement
84%
Felt it working within an hour
Survey results reflect real world experiences from buyers who completed our post purchase questionnaire.
My Go-To for Staying Healthy
“Holoimmune helps me so much with not getting sick!! I get sick continuously unless I take holoimmune. When I take holoimmune, I feel amazing and healthy!!”
You wash your hands.
You take your vitamins.
And you still get knocked out by every bug your kids bring home.
Your innate immune system needs more than "support"—it needs training. HoloImmune pairs M-Gard® beta glucan with three paraprobiotics to prime your immune response at the source: your gut. Beta glucan activates macrophages and NK cells. Paraprobiotics reinforce gut immune signaling and calm over active responses to allergens. Together, they give your body a faster, smarter first line of defense.
Thoughtfully Designed For Maximum Benefits
Here's inner details that make us better than the rest
Think of Immuse®️ as immune leadership training. It targets plasmacytoid dendritic cells (pDCs)—rare coordinator cells that most supplements completely ignore. These cells bridge your innate and adaptive immune systems, helping your body respond appropriately rather than overreact. Backed by 30 published studies, Immuse showed measurable pDC activation and fewer sick days in trials with athletes—in just 13 days. This isn't generic immune support. It's command-level optimization.
L-92®️ teaches your immune system when not to fight. Allergies, skin reactions, food sensitivities—these signal an overreactive Th1/Th2 response, not a weak immune system. L-92 recalibrates this at the source, training gut dendritic cells to reduce unnecessary over reactions. Clinical trials showed improved nasal and skin symptoms in 8 weeks, with measurable drops in bad health markers. Studied since 1985—this is immune discernment, not just immune support.
Immuno-LP20®️ comes from an unlikely source: narezushi, a fermented fish dish that's nourished Southeast Asian communities for centuries. Science now explains why. This strain is unusually rich in lipoteichoic acids—compounds that activate IL-12 and strengthen Th1 immunity, your body's primary defense against viruses. In a 12-week study, people under high stress who took L-137 got sick less often, recovered faster, and needed less medication—with benefits increasing over time. This is a daily driver, not a sick-day supplement.
M-Gard®️ is beta glucan that actually works. Most don't—wrong structure, wrong source, no immune recognition. M-Gard is purified beta-1,3/1,6-glucan from baker's yeast, produced in Norway using a patented process that preserves the branching pattern your immune cells respond to. It triggers "trained immunity" in macrophages and supports secretory IgA in your gut—the shield layer where immune decisions start. 88 published studies. We're not just signaling immune pathways; we're supporting the terrain where immune decisions begin.
Why 65,372+ trust Healthy Gut
- Emily
– Kristina
– Elizabeth B.
– Kristin P.
- Emily
– Kristina
– Elizabeth B.
– Kristin P.
- Emily
– Kristina
– Elizabeth B.
– Kristin P.
How to Take HoloImmune
Start slow
If highly sensitive please start by opening the capsule and sprinkling ¼ of it on your food.
Regular Dose
Most people will have no problem starting with 1 capsule per day.
Clinically Relevant
You may increase the number of capsules per day if under extra stressors.
The Healthy Gut difference
How the 60-Day HoloImmune™ Reset delivers real digestive performance.
Proof that we give a sh*t.
60-Day HoloImmune™ Reset
Your complete gut support.
FAQs
The Total Gut Reset Bundle is for anyone dealing with ongoing or hard-to-pin-down digestive issues who wants a complete, root-cause approach—not a single supplement. It’s ideal if you experience bloating, discomfort after meals, food sensitivities, or inconsistent gut symptoms and suspect more than one system is involved. This protocol is designed to work as a coordinated system, supporting digestion, gut lining integrity, immune balance, and histamine response together to help restore proper gut function and deliver more meaningful, lasting results.
This bundle is structured as a monthly protocol, and many people use it consistently for at least 90 days to fully implement the program as intended. Because everyone is different, results and timing can vary, but consistency tends to matter more than taking products on and off.
The bundle brings together five products designed to support digestion, gut lining integrity, immune balance, and histamine metabolism in one guided monthly protocol. Your subscription includes the Healthy Gut Reset course and a complimentary Gut Strategy session, so you’re not left guessing how to use everything together.
Yes, The Total Gut Reset Bundle is offered as a monthly subscription at $233 including shipping, with the flexibility to modify, skip, or cancel anytime. That makes it easier to stay consistent without feeling locked in.
However, you can select a one time purchase for $318.47+ shipping. Select the One Time Purchase option under the subscription info on this page.
No. All Healthy Gut products are made without gluten, dairy, soy, sugar or GMO's.
Still have questions?
Email us at support@healthygut.com
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