NEW FORMULA
HoloZyme™ 3-Month Supply
Doctor-trusted
Clinically-Studied
"Love this product! I can digest my meals so much better with this enzyme than any other enzymes I've tried."
– Marli
As seen in
Real Results, From Real People
87%
Experienced less bloating after meals
82%
Noticed reduction in gas
91%
Saw noticeable digestion improvement
84%
Felt it working within an hour
Survey results reflect real world experiences from buyers who completed our post purchase questionnaire.
These are the best!
“They are the only enzymes that actually work for me, and I’ve tried many others over the years!”
Eat like a normal human again.
Have the pizza. Enjoy the cake. Order what you really want.
Why? Because food is love.
It’s birthdays, weddings, grandma’s recipe, grabbing lunch with a friend, and the trip you’ve waited two years to take. When your gut is unpredictable, those moments can slowly shrink into “safe meals,” food anxiety, and sitting things out altogether.
HoloZyme was built to help give you some of that freedom back.
So you can focus less on what might go wrong, and more on the people and the moment in front of you.
What HoloZyme Covers:
Gluten & prolamines from wheat, barley, rye, corn, and oats
High FODMAP foods like garlic, onions, and beans
Dairy sugar, protein, and fat - including lactose, casein, and whey
Plus more – protein, fats, starches, sugars, and plant fiber
Every enzyme has a purpose.
Here’s how 15 enzymes work together on the whole plate:
AN-PEP + DPP-IV Protease
Gluten is hard to digest because it’s rich in an amino acid called proline, which creates bonds that our normal digestive enzymes struggle to cut apart.
And there’s something a lot of people don’t know:
Gluten belongs to a larger family of grain proteins called prolamines. Related prolamines are also found in “gluten-free” foods like corn and oats, while other foods like collagen, casein, and tough cuts of meat are also rich in those same stubborn proline bonds.
Which means you can be eating “gluten-free”... but still consuming plenty of proteins that are hard on your gut.
That’s why HoloZyme includes AN-PEP + DPP-IV, two specialized enzymes that help break down those stubborn proline-rich proteins into smaller pieces.*
So you can enjoy gluten when you decide it’s worth it — and still benefit from the extra support even when you don’t.
Helps break down gluten. Not intended to replace a gluten-free diet or to treat or prevent celiac disease.*
Fructanase + Alpha-Galactosidase + Invertase + Lactase
Garlic, onions, beans, broccoli…
A lot of the foods blamed for “sensitive digestion” contain carbohydrates humans simply aren’t great at breaking down on their own.
HoloZyme includes targeted enzymes for several major FODMAP families, helping break them down before gut bacteria get the chance to turn your dinner into hours of gas and bloating.*
Protease + Peptidase
Steak shouldn't sit in your stomach like a brick.
HoloZyme delivers 100,000 HUT of broad-spectrum protease per capsule — plus peptidase to help finish breaking larger protein fragments into smaller pieces.
Plus, the AN-PEP + DPP-IV system adds even more support for difficult proline-rich proteins found in collagen, dairy and other foods.*
Amylase + Maltase + Amyloglucosidase
Bread, rice, pasta, and other starchy foods contain long chains of carbohydrates that need to be chopped into much smaller pieces before your body can use them.
HoloZyme uses multiple enzymes at different stages of that process so your carbs can become fuel instead of sitting around causing digestive trouble.
Lactase + Protease + DPP-IV + Lipase
Dairy isn’t one digestive problem.
Milk and ice cream contain lactose. Cheese and yogurt contain casein and whey. Cream and butter contain fat.
That’s why you need more than just lactase.
HoloZyme gives you 3,000 ALU of lactase per capsule, along with protease, DPP-IV, and lipase to help with the other dairy proteins and fats.
Xylanase + Cellulase + Phytase
Vegetables and plant foods are good for you – but sometimes hard on the gut.
Their nutrients are locked inside tough cell walls and compounds humans don't completely digest on their own.
HoloZyme includes targeted enzymes that help break apart those plant structures so your digestive system can get more out of the healthy food you're already eating.
Enzymes don’t always work alone. Some rely on minerals called cofactors — basically little helpers that power and protect enzyme so they can do their job fully.
That’s why HoloZyme includes CoArmor™, our own patent-pending mineral-powered technology with calcium, magnesium, zinc, manganese, and a trace-mineral complex right alongside the enzymes.
(Previously known as AES Mineral Activation.)
Why 65,372+ trust Healthy Gut
Diane S
Janina F
Celeste T
Linda S.
Diane S
Janina F
Celeste T
Linda S.
Diane S
Janina F
Celeste T
Linda S.
Get the most out of HoloZyme™
Everyday Meals:
1 capsule with your first bites
Your normal breakfast, lunch, or dinner.
Bigger / Richer Meals:
2 capsules with your first bites
Burger + fries, Mexican food, ice cream.
“Going For It” Meals:
3–4 capsules with your first bites
Pasta, pizza, birthday cake.
Pro Tip:
Dose HoloZyme to the meal in front of you. Scrambled eggs don't require the same digestive support as pizza and ice cream. Start with the dose that matches your current routine, then “dose up” when the meal deserves it.
Day 1-3
Meals feel lighter. Less pressure, bloating, "brick stomach."
Week 1-2
More complete breakdown of foods; bowel movements feel more normal and consistent.
Month 1-2
Better nutrient uptake supports energy, thinking, and immune resilience.
Month 5+
Supports long-term digestive ease; users say, "I can eat without the after-effects."
Day 1-3
Meals feel lighter. Less pressure, bloating, "brick stomach."
Week 1-2
More complete breakdown of foods; bowel movements feel more normal and consistent.
Month 1-2
Better nutrient uptake supports energy, thinking, and immune resilience.
Month 5+
Supports long-term digestive ease; users say, "I can eat without the after-effects."
Pro Tip:
Dose HoloZyme to the meal in front of you. Scrambled eggs don't require the same digestive support as pizza and ice cream. Start with the dose that matches your current routine, then “dose up” when the meal deserves it.
The Healthy Gut difference
One formula. Every meal, every time.
HoloZyme helps you eat more of the foods you love — with less gas, bloating, and digestive regret.
Best Seller
Every meal, every time.
Activated enzymes for easier digestion.
FAQs
HoloZyme is for anyone who loves food…
But doesn't always love what happens afterward.
If meals regularly leave you feeling bloated, gassy, overly full or uncomfortable — or you've slowly stopped eating foods like garlic, onions, beans, dairy, grains, restaurant meals and other things you used to enjoy — HoloZyme was built for you.
It's also for people who simply want to get more digestive support from the food they're already eating.
And because HoloZyme now supports gluten + prolamines, it's especially useful when meals get complicated: eating out, traveling, holidays, parties, accidental exposures, or those times you decide the “real thing” is worth it.
Most digestive enzyme products solve one piece of the meal.
A lactase pill handles lactose.
A gluten enzyme handles gluten.
A FODMAP enzyme handles certain fermentable carbohydrates.
But real meals don't show up one problem at a time.
HoloZyme combines 15 enzymes covering 7 major food groups in one formula — including specialized support for gluten + prolamines, FODMAPs, dairy, protein, fats, starches/carbs and fiber.
One formula built for the whole plate.
A lot.
We went from:
12 → 15 enzymes
6 → 7 food groups
2 → 1 capsule per standard serving
We added specialized AN-PEP and DPP-IV support for gluten and other difficult proline-rich proteins, added peptidase, increased lactase by 3.75X, increased protease by 67% per capsule, and packed 31% more active material into each capsule.
Nothing you relied on from the previous enzyme formula was removed.
The only ingredient taken out was L-Leucine, a manufacturing flow agent we no longer need.
Plus, the standard serving went from 2 capsules down to 1 — so you get broader digestive coverage and much more activity packed into each individual capsule, with half as many capsules to swallow.
HoloZyme now contains specialized enzymes that help break down gluten and other proline-rich proteins in the stomach.*
That includes AN-PEP (Tolerase® G), DPP-IV Protease, peptidase and broad-spectrum protease working together.
Important: HoloZyme is not intended to replace a gluten-free diet or to treat or prevent celiac disease.
Because this isn't just about wheat.
Gluten belongs to a larger family of difficult, proline-rich grain proteins called prolamines.
Related proteins are found in:
Corn → zein
Oats → avenin
And other foods such as collagen, gelatin, casein, whey and tough cuts of meat can also be rich in difficult proline bonds.
There's also accidental gluten exposure from restaurant kitchens and manufacturing cross-contact.
So even someone intentionally eating gluten-free may benefit from broader support for proline-rich proteins.
CoArmor™ is Healthy Gut's mineral-powered enzyme technology.
It combines five mineral cofactors — calcium, magnesium, zinc, manganese and a trace-mineral complex — alongside HoloZyme's enzymes.
These cofactors provide “power” to each enzyme, allowing it to work at its full capacity throughout your digestive tract.
This results in digestive power and relief you can actually feel. The difference is noticeable.
Longtime customers may recognize the old name AES. The underlying mineral system remains; CoArmor™ is now Healthy Gut's own trademark as we move forward with research on this specific mineral + enzyme combination.
The old HoloZyme contained 180 capsules because one standard serving required two capsules.
The new HoloZyme contains 90 capsules because one capsule is now a standard serving.
So:
Old: 180 capsules ÷ 2 = 90 servings
New: 90 capsules ÷ 1 = 90 servings
Same number of standard servings, same price.
And the new capsule actually contains 31% more active material than one old capsule.
It's slightly longer, but not wider.
Our new formula uses an elongated 00E capsule that has the same general diameter as the previous capsule while giving us enough room to pack in more active material.
And you're taking one instead of two for the standard serving.
If swallowing capsules is difficult, you can twist it open and mix the powder into a few bites of food, yogurt, applesauce or a smoothie.
Take HoloZyme with the first bites of your meal.
A simple starting guide:
1 capsule: normal everyday meal
2 capsules: bigger or richer meal
3 capsules: restaurant meal / more difficult foods
4 capsules: a very heavy mixed meal
If you used the previous HoloZyme formula, the easiest conversion is: 2 old capsules = 1 new capsule
Need help? Give us a call or email support@healthygut.com and our Practitioners will help you dial in your dose.
HoloZyme is formulated without gluten, dairy, soy, or added sugar and is non-GMO.
The only “Other Ingredient” in HoloZyme is: Hypromellose (capsule).
No. HoloZyme does NOT contain any major allergens, zero sugar, and is GMO free.
Still have questions?
Email us at support@healthygut.com
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